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KMID : 0359920110300060682
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Korean Journal of Nephrology
2011 Volume.30 No. 6 p.682 ~ p.685
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Drug-induced Skin Hyperpigmentation after Usual Dosage of Bismuth-Containing Compound Medication in a Kidney Transplant Patient
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Choi U-Seok
Choi Ha-Nul
Jung Ji-Yong
Chang Jae-Hyun
Jung Woo-Kyung
Lee Hyun-Hee
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Abstract
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A 59-year-old male presented with multiple hyperpigmented skin with hyperkeratotic scaly patches on hands, feet and face. Bismuth containing compound had been prescribed two months before then due to epigastric pain, an adverse effect of steroid pulse therapy for acute rejection of transplanted kidney. Laboratory findings showed acute kidney injury and elevated liver enzyme. He stopped taking bismuth containing compound and all symptoms were gone after two months. Although there is no report on interaction between bismuth and immunosuppressant, it requires precaution to prescribe bismuth containing compounds in transplanted patients with acute kidney injury.
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KEYWORD
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Bismuth, Hyperpigmentation, Kidney transplantation
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